Histologic and histomorphometric evaluation of new zirconia-based ceramic dental implants: A preclinical study in dogs

Healing of soft tissues and improvement aesthetics have become major research objectives in implantology renewed the interest for ceramics implants. The aim this study was to evaluate pre-clinical performance screw-shaped sandblasted-etched implants processed from an innovative zirconia-based ceramic composite, comparison titanium. Twenty-four twenty-four titanium dental were tested a split-mouth design six Beagle dogs. Surface topographies investigated by confocal microscopy. Local tissue effects evaluated at 4 13 weeks after implantation through histology. An ANOVA statistical analysis (5% risk; p < 0.05) performed compare peri-implant quantitative histomorphometric parameters on buccal lingual sides, including Bone Implant Contact (BIC) among test groups time-periods. Titanium presented respectively moderate minimal roughness. After weeks, showed inflammatory response close At both period time there no significant difference between terms BIC values (mean ± SD) or sides when combining + (respectively ceramic, 68.4 14.7 % 75.0 13.5 92.0 8.6 86.1 13.8 weeks). Within limits present study, it can be concluded that newly developed composite similar biocompatibility osseointegration those observed These results corroborate potential use these new oral implantology.